COVID19 Magnesium
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It is early to shout out an idea but it takes time to read the literature as to give a valid academic explanation. Facts will be added on this page as I get them. | It is early to shout out an idea but it takes time to read the literature as to give a valid academic explanation. Facts will be added on this page as I get them. | ||
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| + | The current bibliography on Covid x Magnesium is quite poor herewego: [http://www.moremed.org/SiteSearch.php?S1=%28covid19+OR+covid-19+OR+covid19+OR+sars-cov2+OR+sars-cov-2+OR+2019-ncov+OR+2019ncov%29&S2=trpm7+OR+magnesium&S3=&submit=submit&px1=proxy.nationallizenzen.de&px2=&px3=&px4=&R=all&Y0=1500&Y1=2025 on moremed.org] | ||
* In the influenza papers there are some which make it inappropriate to eliminate the macrophages (remain to be read). This in mind. | * In the influenza papers there are some which make it inappropriate to eliminate the macrophages (remain to be read). This in mind. | ||
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* (1050 items) [http://www.kidney.de/write/PMCmedVIP_c19_div01.html selected from (1)...(7) by title] (top 450 items from this) [http://www.kidney.de/write/PMCmedVIP_C19_div01_subXX.html here] | * (1050 items) [http://www.kidney.de/write/PMCmedVIP_c19_div01.html selected from (1)...(7) by title] (top 450 items from this) [http://www.kidney.de/write/PMCmedVIP_C19_div01_subXX.html here] | ||
| + | On Chloroquine X Magnesium deficiency, effect on cytokines | ||
| + | {{tp|p=8460675|t=Modulation of cytokines and myocardial lesions by vitamin E and chloroquine in a Mg-deficient rat model.|c=}} | ||
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| + | Other therapeutic agents targeting similar pathways are shown ''[http://house-of-papers.com/hop/index.php?title=COVID19_NFKB here]'' | ||
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| + | * (8) [http://www.moremed.org/SiteSearch.php?S1=trpm6+OR+trpm7+OR+trpm-6+OR+trpm-7+OR+transient+receptor+potential+m+6+OR+transient+receptor+potential+m+7&S2=&S3=&submit=submit&px1=proxy.nationallizenzen.de&px2=&px3=&px4=&R=all&Y0=1500&Y1=2025 pubmed trpm channel receptor] | ||
| + | * (450 items on trpm7,XX /X) [http://www.kidney.de/write/PMCmedVIP_trpm7_XX.html XX], [http://www.kidney.de/write/PMCmedVIP_trpm7_X.html X] | ||
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| + | {{tp|p=32047249|t=2020. TRPM7 contributes to progressive nephropathy |pdf=|usr=}} | ||
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aufsichtsbehörde da ich arzt bin www.aeksa.de, www.kvsa.de | aufsichtsbehörde da ich arzt bin www.aeksa.de, www.kvsa.de | ||
magnesium ist diätergänzungsmittel... | magnesium ist diätergänzungsmittel... | ||
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| + | ups... this page IS covered in google if you know how to catch it [https://www.google.de/search?newwindow=1&q=twitter%3A+none+gab%3A+%40nephroVIP+fb%3A+none+&oq=twitter%3A+none+gab%3A+%40nephroVIP+fb%3A+none here] | ||
Latest revision as of 15:29, 8 May 2020
I, incidentally, found a paper which described the actions of magnesium on macrophages, nfkb and inflammatory cytokines , after someone noted the small communication on hypercytokinemia in aggressive covid19 courses. Hydrochloroquine made me interested in macrophages so i grabbed the papers on Mphi in Influenza as a deeper investigated model subject to gain basic biological understanding since viruses & lungs are quite away from my subject area nephrology. All threads taken together I would like to arrive at the conclusion:
- (1) put all mankind or all 60plus population on prophylactic oral magnesium supplementation to reach slightly supernormal mg2+ electrolyte levels
- (2) give all intermediate care subjects mgso4 intravenously and apply nebulized mgso4 topically.
- (3) measure mg2+ and ferritin at clinics entry level for post-hoc/ registry analyses
- (4) do any supportive or experimental add-ons as clinically needed and use magnesium as a low-hazard entry-level starting medication.
Covid19 and its following congeners will target mankind for generations not for years. This-years generation has the responsibility to check even the cheapest interventions and prophylaxes.
It is early to shout out an idea but it takes time to read the literature as to give a valid academic explanation. Facts will be added on this page as I get them.
The current bibliography on Covid x Magnesium is quite poor herewego: on moremed.org
- In the influenza papers there are some which make it inappropriate to eliminate the macrophages (remain to be read). This in mind.
- Magnesium, DNase, NETosis might be a topic.
- (1050 items) selected from (1)...(7) by title (top 450 items from this) here
On Chloroquine X Magnesium deficiency, effect on cytokines
| Journal article, free access |
| GET Modulation of cytokines and myocardial lesions by vitamin E and chloroquine in a Mg-deficient rat model. Extract [{{{pdf}}} PDF direct] |
Other therapeutic agents targeting similar pathways are shown here
- (8) pubmed trpm channel receptor
- (450 items on trpm7,XX /X) XX, X
| Journal article, free access |
| GET 2020. TRPM7 contributes to progressive nephropathy Extract [ PDF direct] |
since this webpost is circulated not only by social media but it is addressed also to the institutions, my contact data are
Ossip Groth (Arzt)
Lepser Strasse 54
D 39261 Zerbst
Germany (East), Sachsen-Anhalt
email & phone in individual communications
twitter: none gab: @nephroVIP fb: none
web: www.moremed.org, www.house-of-papers.com, www.kidney.de
aufsichtsbehörde da ich arzt bin www.aeksa.de, www.kvsa.de magnesium ist diätergänzungsmittel...
ups... this page IS covered in google if you know how to catch it here
