Velcalcetide
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| − | {{ | + | {{slink| |t=Velcalcetide for secondary hyperparathyroidism – first line|l=http://www.hsric.nihr.ac.uk/topics/velcalcetide-for-secondary-hyperparathyroidism-first-line/|usr=goo}} | 
| {{tp|p=26290606|t=Critical Cysteine Residues in Both the Calcium-Sensing Receptor and the Allosteric Activator AMG 416 Underlie the Mechanism of Action |pdf=http://molpharm.aspetjournals.org/content/early/2015/08/19/mol.115.098392.full.pdf|usr=|}} | {{tp|p=26290606|t=Critical Cysteine Residues in Both the Calcium-Sensing Receptor and the Allosteric Activator AMG 416 Underlie the Mechanism of Action |pdf=http://molpharm.aspetjournals.org/content/early/2015/08/19/mol.115.098392.full.pdf|usr=|}} | ||
| {{tp|p=23674604|t=Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients |pdf=|usr=|}} | {{tp|p=23674604|t=Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients |pdf=|usr=|}} | ||
Revision as of 06:51, 1 September 2015
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Moremed Velcalcetide Etelcalcetide+OR+{AMG_416}+OR+{KAI_4169}+OR+{ONO_5163}+OR+Telcalcetide+OR+Velcalcetide
Velcalcetide, a novel calcimimetic, is an allosteric activator of casr, the calcium sensitizing receptor and is in development to treat secondary hyperparathyreoidism of chronical renal failure in a way similar to cinacalcet.
| Contents | 
Mechanism of action
| Weblink noncommercial {{{c}}} | 
| Velcalcetide for secondary hyperparathyroidism – first line | 
| Journal article, free access | 
| GET Critical Cysteine Residues in Both the Calcium-Sensing Receptor and the Allosteric Activator AMG 416 Underlie the Mechanism of Action Extract PDF direct | 
| Journal article, free access | 
| GET Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients Extract [ PDF direct] | 
| Journal article, free access | 
| GET Comparison of AMG 416 and cinacalcet in rodent models of uremia Extract PDF direct | 
| Journal article, free access | 
| GET Velcalcetide (AMG 416), a novel peptide agonist of the calcium-sensing receptor, reduces serum parathyroid hormone and FGF23 levels in healthy male subjects Extract PDF direct | 
| Journal article, free access | 
| GET AMG 416 (velcalcetide) is a novel peptide for the treatment of secondary hyperparathyroidism in a single-dose study in hemodialysis patients Extract [ PDF direct] | 
Mentioned in Fulltext
| Journal article, free access | 
| GET The use of fibroblast growth factor 23 testing in patients with kidney disease Extract PDF direct | 
| Journal article, free access | 
| GET Longitudinal FGF23 and Klotho axis characterization in children treated with chronic peritoneal dialysis Extract PDF direct | 
| Journal article, free access | 
| GET Calcimimetics and outcomes in CKD Extract PDF direct | 
Trials
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