Podocyte and Slit Membrane

From HOP house of papers
(Difference between revisions)
Jump to: navigation, search
m (→Regeneration of Podocytes. Intrinsic stem cells. Transdifferentiation.)
m (→ADCK4 (Coq10) - associated FSGS)
 
(27 intermediate revisions by one user not shown)
Line 1: Line 1:
−
{{hoprn|http://www.kidney.de/bdom/Kidney%20%28Podocytes%29.php}} Podocytes
+
{{hoprn|Kidney%20%28Podocytes%29|1}}
−
{{hoprn|http://www.kidney.de/bdom/NPHS1%20Nephrin.php}} Nephrin
+
{{hoprn|NPHS1%20Nephrin}}
−
{{hoprn|http://www.kidney.de/bdom/Neph1.php}}Neph1
+
{{hoprn|Neph1}}
 +
{{hoprn|CD2AP}}
 +
{{hoprn|Podocin}}
 +
{{hoprn|Podocalyxin}}
 +
{{hoprn|Podoplanin}}
  
−
==General aspects==
+
 
 +
==Podocyte==
 +
{{tp|p=12506131|t=Cell biology of the glomerular podocyte |pdf=http://physrev.physiology.org/content/physrev/83/1/253.full.pdf|usr=|}}
 +
{{tp|p=10662721|t=Roles of the podocyte in glomerular function |pdf=http://ajprenal.physiology.org/content/ajprenal/278/2/F173.full.pdf|usr=|}}
 
{{tp|p=20542138|t=The glomerulus--a view from the outside--the podocyte |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=20542138&pmc=2910191&ti=The%20glomerulus--a%20view%20from%20the%20outside--the%20podocyte|usr=|}}
 
{{tp|p=20542138|t=The glomerulus--a view from the outside--the podocyte |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=20542138&pmc=2910191&ti=The%20glomerulus--a%20view%20from%20the%20outside--the%20podocyte|usr=|}}
 +
{{tp|p=12444221|t=Podocyte biology and response to injury |pdf=http://jasn.asnjournals.org/content/13/12/3005.full.pdf|usr=|}}
 +
{{tp|p=8164413|t=Dysfunctions of cell biological mechanisms of visceral epithelial cell (podocytes) in glomerular diseases |pdf=http://www.nature.com/ki/journal/v45/n2/pdf/ki199439a.pdf|usr=|}}
  
 +
 +
                                            
  
 
==Slit Membrane==
 
==Slit Membrane==
Line 11: Line 22:
 
{{tp|p=21184239|t=Role of the podocyte in proteinuria |pdf=http://link.springer.com/content/pdf/10.1007%2Fs00467-010-1725-5.pdf|usr=|}}
 
{{tp|p=21184239|t=Role of the podocyte in proteinuria |pdf=http://link.springer.com/content/pdf/10.1007%2Fs00467-010-1725-5.pdf|usr=|}}
 
{{tp|p=19244577|t=Lipid-protein interactions along the slit diaphragm of podocytes |pdf=http://jasn.asnjournals.org/content/20/3/473.full.pdf|usr=|}}
 
{{tp|p=19244577|t=Lipid-protein interactions along the slit diaphragm of podocytes |pdf=http://jasn.asnjournals.org/content/20/3/473.full.pdf|usr=|}}
−
{{tp|p=12386277|t=Molecular structure and function of the slit diaphragm: expression of nephrin in  proteinuric states and in developing glomeruli |pdf=http://ndt.oxfordjournals.org/content/17/suppl_9/20.full.pdf|usr=|}}
+
{{tp|p=18391170|t=Properties of the glomerular barrier and mechanisms of proteinuria |pdf=http://physrev.physiology.org/content/physrev/88/2/451.full.pdf|usr=|}}
−
{{tp|p=21776384|t=Tyrosine kinase signaling in kidney glomerular podocytes (fyn, nephrin)|pdf=http://downloads.hindawi.com/journals/jst/2011/317852.pdf|usr=|}}
+
{{tp|p=15153549|t=Signaling at the slit diaphragm |pdf=http://jasn.asnjournals.org/content/15/6/1382.full.pdf|usr=|}}
 +
{{tp|p=17550922|t=Molecular architecture of the glomerular slit diaphragm: lessons learnt for a better understanding of disease pathogenesis |pdf=http://ndt.oxfordjournals.org/content/22/8/2124.full.pdf|usr=|}}
  
 
==Nephrin, Neph1, NPHS1==
 
==Nephrin, Neph1, NPHS1==
 
{{tp|p=10541305|t=Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm |pdf=http://jasn.asnjournals.org/content/10/11/2440.full.pdf|usr=|}}
 
{{tp|p=10541305|t=Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm |pdf=http://jasn.asnjournals.org/content/10/11/2440.full.pdf|usr=|}}
 
{{tp|p=17893108|t=The nephrin-based slit diaphragm: new insight into the signalling platform identifies targets for therapy |pdf=http://ndt.oxfordjournals.org/content/22/12/3408.full.pdf|usr=|}}
 
{{tp|p=17893108|t=The nephrin-based slit diaphragm: new insight into the signalling platform identifies targets for therapy |pdf=http://ndt.oxfordjournals.org/content/22/12/3408.full.pdf|usr=|}}
 +
{{tp|p=19590059|t=A novel role for nephrin in the maintenance of glomerular structure |pdf=http://jasn.asnjournals.org/content/20/8/1661.full.pdf|usr=|}}
 +
{{tp|p=12386277|t=Molecular structure and function of the slit diaphragm: expression of nephrin in  proteinuric states and in developing glomeruli |pdf=http://ndt.oxfordjournals.org/content/17/suppl_9/20.full.pdf|usr=|}}
 +
{{tp|p=21776384|t=Tyrosine kinase signaling in kidney glomerular podocytes (fyn, nephrin)|pdf=http://downloads.hindawi.com/journals/jst/2011/317852.pdf|usr=|}}
 +
 +
==Podocin==
 +
{{tp|p=11786391|t=Focusing on the glomerular slit diaphragm: podocin enters the picture |pdf=http://ajp.amjpathol.org/article/S0002-9440%2810%2964341-6/pdf|usr=|}}
 +
{{tp|p=17348483|t=Renal slit diaphragm--the open zipper and the failing heart |pdf=https://www.ima.org.il/FilesUpload/IMAJ/0/45/22969.pdf|usr=|}}
 +
{{tp|p=14978189|t=Podocin and nephrotic syndrome: implications for the clinician |pdf=http://jasn.asnjournals.org/content/15/3/832.full.pdf|usr=|}}
 +
{{tp|p=11805190|t=Not all in the family: mutations of podocin in sporadic steroid-resistant nephrotic syndrome |pdf=http://jasn.asnjournals.org/content/13/2/577.full.pdf|usr=|}}
 +
  
−
==GBM attachment (Dystroglycan)==
 
−
{{tp|p=19850772|t=Dystroglycan in the molecular diagnosis of the podocytopathies |pdf=http://cjasn.asnjournals.org/content/4/11/1696.full.pdf|usr=|}}
 
  
 
==TRPC6==
 
==TRPC6==
Line 25: Line 45:
 
{{tp|p=21161284|t=TRPC channel modulation in podocytes-inching toward novel treatments for glomerular disease |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=21161284&pmc=3098353&ti=TRPC%20channel%20modulation%20in%20podocytes-inching%20toward%20novel%20treatments%20for%20glomerular%20disease|usr=|}}
 
{{tp|p=21161284|t=TRPC channel modulation in podocytes-inching toward novel treatments for glomerular disease |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=21161284&pmc=3098353&ti=TRPC%20channel%20modulation%20in%20podocytes-inching%20toward%20novel%20treatments%20for%20glomerular%20disease|usr=|}}
 
{{tp|p=17116414|t=TRPC6 in glomerular health and disease: what we know and what we believe |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=17116414&pmc=2705932&ti=TRPC6%20in%20glomerular%20health%20and%20disease:%20what%20we%20know%20and%20what%20we%20believe|usr=|}}
 
{{tp|p=17116414|t=TRPC6 in glomerular health and disease: what we know and what we believe |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=17116414&pmc=2705932&ti=TRPC6%20in%20glomerular%20health%20and%20disease:%20what%20we%20know%20and%20what%20we%20believe|usr=|}}
 +
 +
 +
==GBM attachment (Dystroglycan)==
 +
{{tp|p=19850772|t=Dystroglycan in the molecular diagnosis of the podocytopathies |pdf=http://cjasn.asnjournals.org/content/4/11/1696.full.pdf|usr=|}}
 +
 +
==Podocalyxin==
 +
{{tp|p=19578008|t=The role of podocalyxin in health and disease |pdf=http://jasn.asnjournals.org/content/20/8/1669.full.pdf|usr=|}}
 +
 +
==Podoplanin==
 +
{{tp|p=10048437|t=Podoplanin, a novel 43-kDa membrane protein, controls the shape of podocytes |pdf=http://ndt.oxfordjournals.org/content/14/suppl_1/9.full.pdf|usr=|}}
  
 
==Neuron-type biology of the Podocyte==
 
==Neuron-type biology of the Podocyte==
 
{{tp|p=19628665|t=Signaling at the slit: podocytes chat by synaptic transmission |pdf=http://jasn.asnjournals.org/content/20/9/1862.full.pdf|usr=|}}
 
{{tp|p=19628665|t=Signaling at the slit: podocytes chat by synaptic transmission |pdf=http://jasn.asnjournals.org/content/20/9/1862.full.pdf|usr=|}}
 +
 +
==Podocytes make growth factors==
 +
{{tp|p=20847145|t=VEGF receptors and glomerular function |pdf=http://jasn.asnjournals.org/content/21/10/1599.full.pdf|usr=|}}
 +
  
 
                                            
 
                                            
  
−
==EMT in the Podocyte as equivalent of Slit diaphragm decostruction (Yeah, my idea)==
+
==EMT in the Podocyte as equivalent of Slit diaphragm decostruction==
 +
{{tp|p=12761238|t=Transdifferentiation of epithelial glomerular cells |pdf=http://jasn.asnjournals.org/content/14/suppl_1/S42.full.pdf|usr=|}}
 
{{tp|p=19713303|t=Activation of canonical Wnt signaling meets with podocytopathy (editorial, +snail, -nephrin, in adm nephrosis)|pdf=http://jasn.asnjournals.org/content/20/9/1864.full.pdf|usr=|}}
 
{{tp|p=19713303|t=Activation of canonical Wnt signaling meets with podocytopathy (editorial, +snail, -nephrin, in adm nephrosis)|pdf=http://jasn.asnjournals.org/content/20/9/1864.full.pdf|usr=|}}
 
{{tp|p=19142027|t=Signaling in regulation of podocyte phenotypes |pdf=http://www.karger.com/Article/Pdf/191075|usr=|}}
 
{{tp|p=19142027|t=Signaling in regulation of podocyte phenotypes |pdf=http://www.karger.com/Article/Pdf/191075|usr=|}}
  
 +
==The lost podocyte==
 +
{{tp|p=19293596|t=The pathogenic role of Notch activation in podocytes |pdf=http://www.karger.com/Article/Pdf/209207|usr=|}}
 +
{{tp|p=9734594|t=Progression of glomerular diseases: is the podocyte the culprit?|pdf=http://www.nature.com/ki/journal/v54/n3/pdf/4490297a.pdf|usr=|}}
  
 
==Regeneration of Podocytes. Intrinsic stem cells. Transdifferentiation.==
 
==Regeneration of Podocytes. Intrinsic stem cells. Transdifferentiation.==
Line 50: Line 88:
 
{{tp|p=20333530|t=Hereditary nephrotic syndrome: a systematic approach for genetic testing and a review of associated podocyte gene mutations |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=20333530&pmc=2908444&ti=Hereditary%20nephrotic%20syndrome:%20a%20systematic%20approach%20for%20genetic%20testing%20and%20a%20review%20of%20associated%20podocyte%20gene%20mutations|usr=|}}
 
{{tp|p=20333530|t=Hereditary nephrotic syndrome: a systematic approach for genetic testing and a review of associated podocyte gene mutations |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=20333530&pmc=2908444&ti=Hereditary%20nephrotic%20syndrome:%20a%20systematic%20approach%20for%20genetic%20testing%20and%20a%20review%20of%20associated%20podocyte%20gene%20mutations|usr=|}}
 
{{tp|p=12761234|t=Podocyte differentiation and hereditary proteinuria/nephrotic syndromes |pdf=http://jasn.asnjournals.org/content/14/suppl_1/S22.full.pdf|usr=|}}
 
{{tp|p=12761234|t=Podocyte differentiation and hereditary proteinuria/nephrotic syndromes |pdf=http://jasn.asnjournals.org/content/14/suppl_1/S22.full.pdf|usr=|}}
 +
  
 
==LMX1B - Nail-Patella-syndrome==
 
==LMX1B - Nail-Patella-syndrome==
 
{{tp|p=18253764|t=How are podocytes affected in nail-patella syndrome?|pdf=http://link.springer.com/content/pdf/10.1007%2Fs00467-007-0714-9.pdf|usr=|}}
 
{{tp|p=18253764|t=How are podocytes affected in nail-patella syndrome?|pdf=http://link.springer.com/content/pdf/10.1007%2Fs00467-007-0714-9.pdf|usr=|}}
 +
 +
==ADCK4 (Coq10) - associated FSGS==
 +
for topic relatedness
 +
{{tp|p=25967120|t=2015. ADCK4-Associated Glomerulopathy Causes Adolescence-Onset FSGS |pdf=http://jasn.asnjournals.org/content/early/2015/05/12/ASN.2014121240.long|usr=}}
 +
{{mmlink|l=aarF+domain+containing+kinase+4+OR+ADCK4|t=adck4|c=}}
  
 
==Diabetes mellitus / Insulinresistant state==
 
==Diabetes mellitus / Insulinresistant state==
Line 69: Line 113:
 
{{tp|p=21402784|t=Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2A predisposes mice to glomerulopathy |pdf=http://mcb.asm.org/content/31/10/2162.full.pdf|usr=|}}
 
{{tp|p=21402784|t=Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2A predisposes mice to glomerulopathy |pdf=http://mcb.asm.org/content/31/10/2162.full.pdf|usr=|}}
 
{{tp|p=19590059|t=A novel role for nephrin in the maintenance of glomerular structure (-nfkb)|pdf=http://jasn.asnjournals.org/content/20/8/1661.full.pdf|usr=|}}
 
{{tp|p=19590059|t=A novel role for nephrin in the maintenance of glomerular structure (-nfkb)|pdf=http://jasn.asnjournals.org/content/20/8/1661.full.pdf|usr=|}}
 +
 +
==Weblinks==
 +
{{slink|l=http://www.podonet.org/opencms/opencms/podonet/podonet_en/home|t=Podonet}}
 +
 +

Latest revision as of 11:17, 22 September 2015


Contents

Podocyte

Journal article, free access
GET Cell biology of the glomerular podocyte Extract PDF direct
Journal article, free access
GET Roles of the podocyte in glomerular function Extract PDF direct
Journal article, free access
GET The glomerulus--a view from the outside--the podocyte Extract PDF direct
Journal article, free access
GET Podocyte biology and response to injury Extract PDF direct
Journal article, free access
GET Dysfunctions of cell biological mechanisms of visceral epithelial cell (podocytes) in glomerular diseases Extract PDF direct


                                            

Slit Membrane

Journal article, free access
GET Discovery of the congenital nephrotic syndrome gene discloses the structure of the mysterious molecular sieve of the kidney Extract PDF direct
Journal article, free access
GET Role of the podocyte in proteinuria Extract PDF direct
Journal article, free access
GET Lipid-protein interactions along the slit diaphragm of podocytes Extract PDF direct
Journal article, free access
GET Properties of the glomerular barrier and mechanisms of proteinuria Extract PDF direct
Journal article, free access
GET Signaling at the slit diaphragm Extract PDF direct
Journal article, free access
GET Molecular architecture of the glomerular slit diaphragm: lessons learnt for a better understanding of disease pathogenesis Extract PDF direct

Nephrin, Neph1, NPHS1

Journal article, free access
GET Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm Extract PDF direct
Journal article, free access
GET The nephrin-based slit diaphragm: new insight into the signalling platform identifies targets for therapy Extract PDF direct
Journal article, free access
GET A novel role for nephrin in the maintenance of glomerular structure Extract PDF direct
Journal article, free access
GET Molecular structure and function of the slit diaphragm: expression of nephrin in proteinuric states and in developing glomeruli Extract PDF direct
Journal article, free access
GET Tyrosine kinase signaling in kidney glomerular podocytes (fyn, nephrin) Extract PDF direct

Podocin

Journal article, free access
GET Focusing on the glomerular slit diaphragm: podocin enters the picture Extract PDF direct
Journal article, free access
GET Renal slit diaphragm--the open zipper and the failing heart Extract PDF direct
Journal article, free access
GET Podocin and nephrotic syndrome: implications for the clinician Extract PDF direct
Journal article, free access
GET Not all in the family: mutations of podocin in sporadic steroid-resistant nephrotic syndrome Extract PDF direct


TRPC6

Journal article, free access
GET TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology Extract PDF direct
Journal article, free access
GET TRPC channel modulation in podocytes-inching toward novel treatments for glomerular disease Extract PDF direct
Journal article, free access
GET TRPC6 in glomerular health and disease: what we know and what we believe Extract PDF direct


GBM attachment (Dystroglycan)

Journal article, free access
GET Dystroglycan in the molecular diagnosis of the podocytopathies Extract PDF direct

Podocalyxin

Journal article, free access
GET The role of podocalyxin in health and disease Extract PDF direct

Podoplanin

Journal article, free access
GET Podoplanin, a novel 43-kDa membrane protein, controls the shape of podocytes Extract PDF direct

Neuron-type biology of the Podocyte

Journal article, free access
GET Signaling at the slit: podocytes chat by synaptic transmission Extract PDF direct

Podocytes make growth factors

Journal article, free access
GET VEGF receptors and glomerular function Extract PDF direct


                                            

EMT in the Podocyte as equivalent of Slit diaphragm decostruction

Journal article, free access
GET Transdifferentiation of epithelial glomerular cells Extract PDF direct
Journal article, free access
GET Activation of canonical Wnt signaling meets with podocytopathy (editorial, +snail, -nephrin, in adm nephrosis) Extract PDF direct
Journal article, free access
GET Signaling in regulation of podocyte phenotypes Extract PDF direct

The lost podocyte

Journal article, free access
GET The pathogenic role of Notch activation in podocytes Extract PDF direct
Journal article, free access
GET Progression of glomerular diseases: is the podocyte the culprit? Extract PDF direct

Regeneration of Podocytes. Intrinsic stem cells. Transdifferentiation.

Journal article, free access
GET Glomerular epithelial stem cells: the good, the bad, and the ugly Extract PDF direct
Journal article, free access
GET Transdifferentiation of epithelial glomerular cells Extract PDF direct

                                            

Hereditary diseases at the podocyte and slit membrane

Journal article, free access
GET A proposed taxonomy for the podocytopathies: a reassessment of the primary nephrotic diseases Extract PDF direct
Journal article, free access
GET Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis--a review Extract PDF direct
Journal article, free access
GET Congenital nephrotic syndrome Extract PDF direct
Journal article, free access
GET Transcriptional regulation of podocyte disease Extract PDF direct
Journal article, free access
GET Podocyte differentiation and hereditary proteinuria/nephrotic syndromes Extract PDF direct
Journal article, free access
GET Hereditary nephrotic syndrome: a systematic approach for genetic testing and a review of associated podocyte gene mutations Extract PDF direct
Journal article, free access
GET Podocyte differentiation and hereditary proteinuria/nephrotic syndromes Extract PDF direct


LMX1B - Nail-Patella-syndrome

Journal article, free access
GET How are podocytes affected in nail-patella syndrome? Extract PDF direct

ADCK4 (Coq10) - associated FSGS

for topic relatedness

Journal article, free access
GET 2015. ADCK4-Associated Glomerulopathy Causes Adolescence-Onset FSGS Extract PDF direct
search term via moremed.org '
adck4

Diabetes mellitus / Insulinresistant state

Journal article, free access
GET Role of altered insulin signaling pathways in the pathogenesis of podocyte malfunction and microalbuminuria Extract PDF direct

==Hypertensive nephropathy. ProRenin receptor.

Journal article, free access
GET Involvement of (pro)renin receptor in the glomerular filtration barrier Extract PDF direct

Unsorted

Journal article, free access
GET 1985. Podoendin A new cell surface protein of the podocyte and endothelium Extract PDF direct
Journal article, free access
GET Initial insight on the determinants of podocyte polarity Extract PDF direct
Journal article, free access
GET Podocyte-specific gene mutations are coming of age Extract PDF direct
Journal article, free access
GET Are podocytes passive or provocative in proteinuric glomerular pathology? Extract PDF direct
Journal article, free access
GET Stressed-out podocytes in diabetes? Extract PDF direct
Journal article, free access
GET TRB3 is stimulated in diabetic kidneys, regulated by the ER stress marker CHOP, and is a suppressor of podocyte MCP-1 Extract PDF direct
Journal article, free access
GET Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2A predisposes mice to glomerulopathy Extract PDF direct
Journal article, free access
GET A novel role for nephrin in the maintenance of glomerular structure (-nfkb) Extract PDF direct

Weblinks

Weblink noncommercial {{{c}}}
Podonet

Retrieved from "http://house-of-papers.com/hop/index.php?title=Podocyte_and_Slit_Membrane&oldid=579"
Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox
Blogverzeichnis - Blog Verzeichnis bloggerei.deBlogverzeichnis