Template:Dgfn2015 Mo 08:15 Glycocalyx im Glomerulus
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==Glycocalyx im Glomerulus== | ==Glycocalyx im Glomerulus== | ||
| − | === | + | ===What is the role of the endothelial glycocalyx in renal diseases?=== |
| + | [http://nephrologie.conference2web.com/users/7603 Rabelink T] | ||
| + | |||
{{tp|p=25673809|t=2015. A microscopic view on the renal endothelial glycocalyx |pdf=http://ajprenal.physiology.org/content/308/9/F956.full.pdf|usr=}} | {{tp|p=25673809|t=2015. A microscopic view on the renal endothelial glycocalyx |pdf=http://ajprenal.physiology.org/content/308/9/F956.full.pdf|usr=}} | ||
| − | jvascres 2009 | + | jvascres 2009 megens '''this reference does not exist.''' |
{{tp|p=23595539|t=2013. Glycopolymer probes of signal transduction |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=23595539&pmc=3808984&ti=Glycopolymer%20probes%20of%20signal%20transduction|usr=}} | {{tp|p=23595539|t=2013. Glycopolymer probes of signal transduction |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=23595539&pmc=3808984&ti=Glycopolymer%20probes%20of%20signal%20transduction|usr=}} | ||
| Line 22: | Line 24: | ||
{{tp|p=22106160|t=2012. Heparanase is essential for the development of diabetic nephropathy in mice |pdf=http://diabetes.diabetesjournals.org/content/61/1/208.full.pdf|usr=}} | {{tp|p=22106160|t=2012. Heparanase is essential for the development of diabetic nephropathy in mice |pdf=http://diabetes.diabetesjournals.org/content/61/1/208.full.pdf|usr=}} | ||
| − | + | {{slink|l=http://www.ncbi.nlm.nih.gov/pubmed/?term=atrasentan+AND+heparanase|t=Atrasentan x Heparanase|c=paper pending}} | |
{{slink|l=http://www.nierstichting.nl/professionals/projecten/consortium-glycoren-work-package-1-ultrastructure-and-its-regulation-of-the-glomerular-endothelial-glycocalyx-in-health-and-proteinuric-disease-3375/ |t=Glycoren consortium |c= }} | {{slink|l=http://www.nierstichting.nl/professionals/projecten/consortium-glycoren-work-package-1-ultrastructure-and-its-regulation-of-the-glomerular-endothelial-glycocalyx-in-health-and-proteinuric-disease-3375/ |t=Glycoren consortium |c= }} | ||
| + | |||
| + | ===Rolle von Lipiden an der Schlitzmembran des glomerulären Filters === | ||
| + | [http://nephrologie.conference2web.com/users/7604 Hagmann-H] | ||
| + | {{tp|p=19244577|t=2009. Lipid-protein interactions along the slit diaphragm of podocytes |pdf=http://jasn.asnjournals.org/content/20/3/473.full.pdf|usr=}} | ||
| + | {{tp|p=17079490|t=2006. Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels |pdf=http://www.pnas.org/content/103/46/17079.full.pdf|usr=}} | ||
| + | {{tp|p=23948707|t=2013. NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex |pdf=http://ajpcell.physiology.org/content/305/9/C960.full.pdf|usr=}} | ||
| + | {{tp|p=23835338|t=2013. Cyclodextrin protects podocytes in diabetic kidney disease |pdf=http://diabetes.diabetesjournals.org/content/62/11/3817.full.pdf|usr=}} | ||
| + | {{tp|p=24861084|t=2014. Lipid biology of the podocyte--new perspectives offer new opportunities |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=24861084&pmc=4386893&ti=Lipid%20biology%20of%20the%20podocyte--new%20perspectives%20offer%20new%20opportunities|usr=}} | ||
| + | {{tp|p=24421402|t=2014. Breaking the chain at the membrane: paraoxonase 2 counteracts lipid peroxidation at the plasma membrane |pdf=http://www.fasebj.org/content/28/4/1769.full.pdf|usr=}} | ||
| + | |||
| + | ===The endothelial glycocalyx is a protective barrier against salt-induced vascular - Inflammation=== | ||
| + | [http://nephrologie.conference2web.com/users/9537 Kusche-Vihrog-K] | ||
| + | |||
| + | |||
| + | Dieser Webcast ist noch nicht verfügbar. Kann dann später die refs prüfen. | ||
| + | |||
| + | ???jct 2010/2013 ?fasib | ||
| + | {{tp|p=24868010|t=2014. Feedforward activation of endothelial ENaC by high sodium |pdf=http://www.fasebj.org/content/28/9/4015.short|usr=}} | ||
| + | ???nrn 2014 ??werneck/wernoch | ||
| + | ???j c... hypertens 2013 ?jyggle | ||
| + | ???pflügers a 2011 ??jyggle | ||
| + | ejp 2011 oberleithner | ||
| + | |||
| + | ===Pathogenetische Bedeutung von Lipiden beim M. Fabry=== | ||
| + | [http://nephrologie.conference2web.com/users/7606 Porubsky-S] | ||
| + | |||
| + | vdgp 1950 scriba 34 221 nicht im pubmed. nicht im web. muß man kopieren gehen. | ||
| + | |||
| + | |||
| + | {{tp|p=13536474|t=1958. The renal lesion in angiokeratoma corporis diffusum |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=13536474&pmc=2028866&ti=The%20renal%20lesion%20in%20angiokeratoma%20corporis%20diffusum|usr=}} | ||
| + | {{utp|p=14007664|t=1962. Angiokeratoma corporis diffusum A clinical study of eight affected families |pdf=http://qjmed.oxfordjournals.org/content/31/2/177.full-text.pdf|usr=}} | ||
| + | {{tp|p=14081947|t=1963. FABRY S DISEASE: CLASSIFICATION AS A SPHINGOLIPIDOSIS AND PARTIAL CHARACTERIZATION OF A NOVEL GLYCOLIPID |pdf=http://www.jbc.org/content/238/9/PC3148.full.pdf|usr=}} | ||
| + | {{tp|p=22875802|t=2012. Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells |pdf=http://www.jimmunol.org/content/189/6/3007.full.pdf|usr=}} | ||
| + | {{tp|p=17372206|t=2007. Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency |pdf=http://www.pnas.org/content/104/14/5977.full.pdf|usr=}} | ||
| + | {{tp|p=24909663|t=2014. Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure |pdf=http://onlinelibrary.wiley.com/doi/10.1002/path.4388/epdf|usr=}} | ||
| + | {{tp|p=24992926|t=2014. Depletion of globosides and isoglobosides fully reverts the morphologic phenotype of Fabry disease |pdf=http://link.springer.com/content/pdf/10.1007%2Fs00441-014-1922-9.pdf|usr=}} | ||
| + | {{tp|p=24335674|t=2014. Globotriaosylceramide induces endothelial dysfunction in fabry disease |pdf=http://atvb.ahajournals.org/content/34/1/2.full.pdf|usr=}} | ||
| + | {{tp|p=24158513|t=2014. Globotriaosylceramide induces lysosomal degradation of endothelial KCa3 1 in fabry disease |pdf=http://atvb.ahajournals.org/content/34/1/81.full.pdf|usr=}} | ||
| + | {{tp|p=20971723|t=2011. Globotriaosylceramide leads to K(Ca)3 1 channel dysfunction: a new insight into endothelial dysfunction in Fabry disease |pdf=http://cardiovascres.oxfordjournals.org/content/cardiovascres/89/2/290.full.pdf|usr=}} | ||
| + | {{tp|p=23691056|t=2013. Dysregulated autophagy contributes to podocyte damage in Fabry s disease |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=23691056&pmc=3656911&ti=Dysregulated%20autophagy%20contributes%20to%20podocyte%20damage%20in%20Fabry%20s%20disease|usr=}} | ||
| + | {{utp|p=24239767|t=2014. Gaucher disease and Fabry disease: new markers and insights in pathophysiology for two distinct glycosphingolipidoses |pdf=http://www.sciencedirect.com/science/article/pii/S1388198113002461|usr=}} | ||
| + | {{tp|p=20504837|t=2011. Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy |pdf=http://ndt.oxfordjournals.org/content/26/6/1797.full.pdf|usr=}} | ||
| + | {{tp|p=26291612|t=2015. Epithelial-Mesenchymal Transition in Kidney Tubular Epithelial Cells Induced by Globotriaosylsphingosine and Globotriaosylceramide |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=26291612&pmc=4546309&ti=Epithelial-Mesenchymal%20Transition%20in%20Kidney%20Tubular%20Epithelial%20Cells%20Induced%20by%20Globotriaosylsphingosine%20and%20Globotriaosylceramide|usr=}} | ||
| + | {{utp|p=23452955|t=2013. Fabry disease peripheral blood immune cells release inflammatory cytokines: role of globotriaosylceramide |pdf=http://www.sciencedirect.com/science/article/pii/S1096719213000462|usr=}} | ||
| + | {{tp|p=9122231|t=1997. alpha-Galactosidase A deficient mice: a model of Fabry disease |pdf=http://www.pnas.org/content/94/6/2540.full.pdf|usr=}} | ||
| + | {{tp|p=10339603|t=1999. Aging accentuates and bone marrow transplantation ameliorates metabolic defects in Fabry disease mice |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=10339603&pmc=26897&ti=Aging%20accentuates%20and%20bone%20marrow%20transplantation%20ameliorates%20metabolic%20defects%20in%20Fabry%20disease%20mice|usr=}} | ||
| + | {{tp|p=20961863|t=2011. Increased globotriaosylceramide levels in a transgenic mouse expressing human alpha1,4-galactosyltransferase and a mouse model for treating Fabry disease |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=20961863&pmc=3031308&ti=Increased%20globotriaosylceramide%20levels%20in%20a%20transgenic%20mouse%20expressing%20human%20alpha1,4-galactosyltransferase%20and%20a%20mouse%20model%20for%20treating%20Fabry%20disease|usr=}} | ||
| + | {{tp|p=24094090|t=2013. A symptomatic Fabry disease mouse model generated by inducing globotriaosylceramide synthesis |pdf=http://www.biochemj.org/content/ppbiochemj/456/3/373.full.pdf|usr=}} | ||
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| + | folgt. | ||
Latest revision as of 08:59, 23 September 2015
Contents |
Glycocalyx im Glomerulus
What is the role of the endothelial glycocalyx in renal diseases?
| Journal article, free access |
| GET 2015. A microscopic view on the renal endothelial glycocalyx Extract PDF direct |
jvascres 2009 megens this reference does not exist.
| Journal article, free access |
| GET 2013. Glycopolymer probes of signal transduction Extract PDF direct |
| Journal Paper, restricted access |
| GET 2014. Demystifying heparan sulfate-protein interactions Extract PDF direct |
| Journal article, free access |
| GET 2007. Emerging glycomics technologies Extract PDF direct |
| Journal article, free access |
| GET 2013. Glomerular endothelial surface layer acts as a barrier against albumin filtration Extract PDF direct |
| Journal article, free access |
| GET 2006. VE-cadherin-CreERT2 transgenic mouse: a model for inducible recombination in the endothelium Extract PDF direct |
| Journal article, free access |
| GET 2006. VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells Extract PDF direct |
| Journal article, free access |
| GET 2009. Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb Extract PDF direct |
| Journal Paper, restricted access |
| GET 2011. The glomerular endothelial cell coat is essential for glomerular filtration Extract PDF direct |
submitted/notavailable nrn 2015 rabelink
| Journal article, free access |
| GET 2008. Heparan sulfate domains on cultured activated glomerular endothelial cells mediate leukocyte trafficking Extract PDF direct |
| Journal article, free access |
| GET 2014. Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis Extract PDF direct |
| Journal Paper, restricted access |
| GET 2014. Podocyte-specific deletion of NDST1, a key enzyme in the sulfation of heparan sulfate glycosaminoglycans, leads to abnormalities in podocyte organization in vivo Extract PDF direct |
| Journal article, free access |
| GET 2007. Heparanase in glomerular diseases Extract PDF direct |
| Journal article, free access |
| GET 2012. Heparanase is essential for the development of diabetic nephropathy in mice Extract PDF direct |
| Weblink noncommercial paper pending |
| Atrasentan x Heparanase |
| Weblink noncommercial ' |
| Glycoren consortium |
Rolle von Lipiden an der Schlitzmembran des glomerulären Filters
| Journal article, free access |
| GET 2009. Lipid-protein interactions along the slit diaphragm of podocytes Extract PDF direct |
| Journal article, free access |
| GET 2006. Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels Extract PDF direct |
| Journal article, free access |
| GET 2013. NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex Extract PDF direct |
| Journal article, free access |
| GET 2013. Cyclodextrin protects podocytes in diabetic kidney disease Extract PDF direct |
| Journal article, free access |
| GET 2014. Lipid biology of the podocyte--new perspectives offer new opportunities Extract PDF direct |
| Journal article, free access |
| GET 2014. Breaking the chain at the membrane: paraoxonase 2 counteracts lipid peroxidation at the plasma membrane Extract PDF direct |
The endothelial glycocalyx is a protective barrier against salt-induced vascular - Inflammation
Dieser Webcast ist noch nicht verfügbar. Kann dann später die refs prüfen.
???jct 2010/2013 ?fasib
| Journal article, free access |
| GET 2014. Feedforward activation of endothelial ENaC by high sodium Extract PDF direct |
???nrn 2014 ??werneck/wernoch ???j c... hypertens 2013 ?jyggle ???pflügers a 2011 ??jyggle ejp 2011 oberleithner
Pathogenetische Bedeutung von Lipiden beim M. Fabry
vdgp 1950 scriba 34 221 nicht im pubmed. nicht im web. muß man kopieren gehen.
| Journal article, free access |
| GET 1958. The renal lesion in angiokeratoma corporis diffusum Extract PDF direct |
| Journal Paper, restricted access |
| GET 1962. Angiokeratoma corporis diffusum A clinical study of eight affected families Extract PDF direct |
| Journal article, free access |
| GET 1963. FABRY S DISEASE: CLASSIFICATION AS A SPHINGOLIPIDOSIS AND PARTIAL CHARACTERIZATION OF A NOVEL GLYCOLIPID Extract PDF direct |
| Journal article, free access |
| GET 2012. Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells Extract PDF direct |
| Journal article, free access |
| GET 2007. Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency Extract PDF direct |
| Journal article, free access |
| GET 2014. Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure Extract PDF direct |
| Journal article, free access |
| GET 2014. Depletion of globosides and isoglobosides fully reverts the morphologic phenotype of Fabry disease Extract PDF direct |
| Journal article, free access |
| GET 2014. Globotriaosylceramide induces endothelial dysfunction in fabry disease Extract PDF direct |
| Journal article, free access |
| GET 2014. Globotriaosylceramide induces lysosomal degradation of endothelial KCa3 1 in fabry disease Extract PDF direct |
| Journal article, free access |
| GET 2011. Globotriaosylceramide leads to K(Ca)3 1 channel dysfunction: a new insight into endothelial dysfunction in Fabry disease Extract PDF direct |
| Journal article, free access |
| GET 2013. Dysregulated autophagy contributes to podocyte damage in Fabry s disease Extract PDF direct |
| Journal Paper, restricted access |
| GET 2014. Gaucher disease and Fabry disease: new markers and insights in pathophysiology for two distinct glycosphingolipidoses Extract PDF direct |
| Journal article, free access |
| GET 2011. Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy Extract PDF direct |
| Journal article, free access |
| GET 2015. Epithelial-Mesenchymal Transition in Kidney Tubular Epithelial Cells Induced by Globotriaosylsphingosine and Globotriaosylceramide Extract PDF direct |
| Journal Paper, restricted access |
| GET 2013. Fabry disease peripheral blood immune cells release inflammatory cytokines: role of globotriaosylceramide Extract PDF direct |
| Journal article, free access |
| GET 1997. alpha-Galactosidase A deficient mice: a model of Fabry disease Extract PDF direct |
| Journal article, free access |
| GET 1999. Aging accentuates and bone marrow transplantation ameliorates metabolic defects in Fabry disease mice Extract PDF direct |
| Journal article, free access |
| GET 2011. Increased globotriaosylceramide levels in a transgenic mouse expressing human alpha1,4-galactosyltransferase and a mouse model for treating Fabry disease Extract PDF direct |
| Journal article, free access |
| GET 2013. A symptomatic Fabry disease mouse model generated by inducing globotriaosylceramide synthesis Extract PDF direct |
folgt.
