Velcalcetide
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Revision as of 06:45, 1 September 2015
- HOP_Nephrology_Index shows all Nephrology topics
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Moremed Velcalcetide Etelcalcetide+OR+{AMG_416}+OR+{KAI_4169}+OR+{ONO_5163}+OR+Telcalcetide+OR+Velcalcetide
Velcalcetide, a novel calcimimetic, is an allosteric activator of casr, the calcium sensitizing receptor and is in development to treat secondary hyperparathyreoidism of chronical renal failure in a way similar to cinacalcet.
Contents |
Mechanism of action
Journal article, free access |
GET Velcalcetide for secondary hyperparathyroidism – first line [[expm{{{p}}}| Extract]] PDF directcontrib: goo |
Journal article, free access |
GET Critical Cysteine Residues in Both the Calcium-Sensing Receptor and the Allosteric Activator AMG 416 Underlie the Mechanism of Action Extract PDF direct |
Journal article, free access |
GET Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients Extract [ PDF direct] |
Journal article, free access |
GET Comparison of AMG 416 and cinacalcet in rodent models of uremia Extract PDF direct |
Journal article, free access |
GET Velcalcetide (AMG 416), a novel peptide agonist of the calcium-sensing receptor, reduces serum parathyroid hormone and FGF23 levels in healthy male subjects Extract PDF direct |
Journal article, free access |
GET AMG 416 (velcalcetide) is a novel peptide for the treatment of secondary hyperparathyroidism in a single-dose study in hemodialysis patients Extract [ PDF direct] |
Mentioned in Fulltext
Journal article, free access |
GET The use of fibroblast growth factor 23 testing in patients with kidney disease Extract PDF direct |
Journal article, free access |
GET Longitudinal FGF23 and Klotho axis characterization in children treated with chronic peritoneal dialysis Extract PDF direct |
Journal article, free access |
GET Calcimimetics and outcomes in CKD Extract PDF direct |
Trials
Wikipedia
Wikipedia |
en-wiki |
Books