Riociguat
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==Core OA papers on Riociguat== | ==Core OA papers on Riociguat== | ||
| + | {{tp|p=25395817|t=2014. Riociguat (adempas): a novel agent for the treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=25395817&pmc=4218670&ti=Riociguat%20(adempas):%20a%20novel%20agent%20for%20the%20treatment%20of%20pulmonary%20arterial%20hypertension%20and%20chronic%20thromboembolic%20pulmonary%20hypertension%20|usr=}} | ||
{{tp|p=25709345|t=2015. Riociguat: Something new in pulmonary hypertension therapeutics?|pdf=http://www.jpharmacol.com/temp/JPharmacolPharmacother613-3656504_100925.pdf|usr=}} | {{tp|p=25709345|t=2015. Riociguat: Something new in pulmonary hypertension therapeutics?|pdf=http://www.jpharmacol.com/temp/JPharmacolPharmacother613-3656504_100925.pdf|usr=}} | ||
{{tp|p=25395817|t=2014. Riociguat (adempas): a novel agent for the treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=25395817&pmc=4218670&ti=Riociguat%20%28adempas%29:%20a%20novel%20agent%20for%20the%20treatment%20of%20pulmonary%20arterial%20hypertension%20and%20chronic%20thromboembolic%20pulmonary%20hypertension|usr=}} | {{tp|p=25395817|t=2014. Riociguat (adempas): a novel agent for the treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=25395817&pmc=4218670&ti=Riociguat%20%28adempas%29:%20a%20novel%20agent%20for%20the%20treatment%20of%20pulmonary%20arterial%20hypertension%20and%20chronic%20thromboembolic%20pulmonary%20hypertension|usr=}} | ||
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{{tp|p=23883377|t=2013. Riociguat for the treatment of chronic thromboembolic pulmonary hypertension |pdf=http://www.nejm.org/doi/pdf/10.1056/NEJMoa1209657|usr=}} | {{tp|p=23883377|t=2013. Riociguat for the treatment of chronic thromboembolic pulmonary hypertension |pdf=http://www.nejm.org/doi/pdf/10.1056/NEJMoa1209657|usr=}} | ||
| + | |||
==General outline of Pulmonary Hypertension== | ==General outline of Pulmonary Hypertension== | ||
| + | {{tp|p=23978639|t=2013. Recent progress in the diagnosis and management of chronic thromboembolic pulmonary hypertension |pdf=http://www.respiratoryinvestigation.com/article/S2212-5345(13)00011-7/pdf|usr=}} | ||
| + | {{tp|p=26336595|t=2015. Medical treatment update on pulmonary arterial hypertension |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=26336595&pmc=4549695&ti=Medical%20treatment%20update%20on%20pulmonary%20arterial%20hypertension%20|usr=}} | ||
| + | {{tp|p=26219978|t=2015. The molecular targets of approved treatments for pulmonary arterial hypertension |pdf=http://thorax.bmj.com/content/early/2015/07/28/thoraxjnl-2015-207170.full.pdf+html|usr=}} | ||
{{tp|p=26028639|t=2015. Pharmacological therapy for patients with chronic thromboembolic pulmonary hypertension |pdf=http://err.ersjournals.com/content/24/136/272.full.pdf|usr=}} | {{tp|p=26028639|t=2015. Pharmacological therapy for patients with chronic thromboembolic pulmonary hypertension |pdf=http://err.ersjournals.com/content/24/136/272.full.pdf|usr=}} | ||
{{tp|p=25411669|t=2014. Drug Therapy for Chronic Thromboembolic Pulmonary Hypertension: A Review of the Comparative Clinical Effectiveness|pdf=http://www.ncbi.nlm.nih.gov/books/NBK253756/pdf/Bookshelf_NBK253756.pdf|usr=}} | {{tp|p=25411669|t=2014. Drug Therapy for Chronic Thromboembolic Pulmonary Hypertension: A Review of the Comparative Clinical Effectiveness|pdf=http://www.ncbi.nlm.nih.gov/books/NBK253756/pdf/Bookshelf_NBK253756.pdf|usr=}} | ||
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{{tp|p=25077002|t=2014. Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Medical and surgical management for pulmonary arterial hypertension |pdf=http://www.thoracicmedicine.org/temp/AnnThoracMed9579-3569344_095453.pdf|usr=}} | {{tp|p=25077002|t=2014. Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Medical and surgical management for pulmonary arterial hypertension |pdf=http://www.thoracicmedicine.org/temp/AnnThoracMed9579-3569344_095453.pdf|usr=}} | ||
{{tp|p=23997048|t=2013. Therapies for pulmonary arterial hypertension: where are we today, where do we go tomorrow?|pdf=http://err.ersjournals.com/content/errev/22/129/217.full.pdf|usr=}} | {{tp|p=23997048|t=2013. Therapies for pulmonary arterial hypertension: where are we today, where do we go tomorrow?|pdf=http://err.ersjournals.com/content/errev/22/129/217.full.pdf|usr=}} | ||
| − | + | {{tp|p=25309604|t=2014. Respiratory review of 2014: pulmonary thromboembolism |pdf=http://www.e-trd.org/upload/abstract/files/v77n03105.pdf|usr=}} | |
| − | + | {{tp|p=24401129|t=2014. Novel and emerging therapies for pulmonary hypertension |pdf=http://www.atsjournals.org/doi/pdf/10.1164/rccm.201308-1543PP|usr=}} | |
==Mechanism of action== | ==Mechanism of action== | ||
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| − | + | ||
| Line 27: | Line 32: | ||
| + | {{tp|p=24738736|t=2014. Stimulation of soluble guanylate cyclase prevents cigarette smoke-induced pulmonary hypertension and emphysema |pdf=http://www.atsjournals.org/doi/pdf/10.1164/rccm.201311-2037OC|usr=}} | ||
| + | {{tp|p=26064454|t=2015. Acute effects of riociguat in borderline or manifest pulmonary hypertension associated with chronic obstructive pulmonary disease |pdf=http://www.jstor.org/stable/pdfplus/10.1086/680214.pdf?acceptTC=true&jpdConfirm=true|usr=}} | ||
| + | {{tp|p=26011408|t=2015. Change of right heart size and function by long-term therapy with riociguat in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension |pdf=http://www.internationaljournalofcardiology.com/article/S0167-5273(15)01168-7/pdf|usr=}} | ||
| + | |||
| − | {{tp|p= | + | ==Nephrology-related data== |
| + | {{tp|p=21789188|t=2011. Soluble guanylate cyclase stimulation prevents fibrotic tissue remodeling and improves survival in salt-sensitive Dahl rats |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=21789188&pmc=3138745&ti=Soluble%20guanylate%20cyclase%20stimulation%20prevents%20fibrotic%20tissue%20remodeling%20and%20improves%20survival%20in%20salt-sensitive%20Dahl%20rats%20|usr=}} | ||
| + | |||
| + | ==Books== | ||
| + | |||
Revision as of 14:39, 26 October 2015
Contents |
Core OA papers on Riociguat
| Journal article, free access |
| GET 2014. Riociguat (adempas): a novel agent for the treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension Extract PDF direct |
| Journal article, free access |
| GET 2015. Riociguat: Something new in pulmonary hypertension therapeutics? Extract PDF direct |
| Journal article, free access |
| GET 2014. Riociguat (adempas): a novel agent for the treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension Extract PDF direct |
| Journal article, free access |
| GET 2013. Riociguat for the treatment of pulmonary arterial hypertension Extract PDF direct |
| Journal article, free access |
| GET 2013. Riociguat for the treatment of chronic thromboembolic pulmonary hypertension Extract PDF direct |
General outline of Pulmonary Hypertension
| Journal article, free access |
| GET 2013. Recent progress in the diagnosis and management of chronic thromboembolic pulmonary hypertension Extract PDF direct |
| Journal article, free access |
| GET 2015. Medical treatment update on pulmonary arterial hypertension Extract PDF direct |
| Journal article, free access |
| GET 2015. The molecular targets of approved treatments for pulmonary arterial hypertension Extract PDF direct |
| Journal article, free access |
| GET 2015. Pharmacological therapy for patients with chronic thromboembolic pulmonary hypertension Extract PDF direct |
| Journal article, free access |
| GET 2014. Drug Therapy for Chronic Thromboembolic Pulmonary Hypertension: A Review of the Comparative Clinical Effectiveness Extract PDF direct |
| Journal article, free access |
| GET 2014. Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Chronic thromboembolic pulmonary hypertension Extract PDF direct |
| Journal article, free access |
| GET 2014. Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Medical and surgical management for pulmonary arterial hypertension Extract PDF direct |
| Journal article, free access |
| GET 2013. Therapies for pulmonary arterial hypertension: where are we today, where do we go tomorrow? Extract PDF direct |
| Journal article, free access |
| GET 2014. Respiratory review of 2014: pulmonary thromboembolism Extract PDF direct |
| Journal article, free access |
| GET 2014. Novel and emerging therapies for pulmonary hypertension Extract PDF direct |
Mechanism of action
| Journal article, free access |
| GET 2010. Riociguat: an upcoming therapy in chronic thromboembolic pulmonary hypertension? Extract PDF direct |
| Journal article, free access |
| GET 2009. Soluble guanylate cyclase stimulation: an emerging option in pulmonary hypertension therapy Extract PDF direct |
| Journal article, free access |
| GET 2008. Expression and function of soluble guanylate cyclase in pulmonary arterial hypertension Extract PDF direct |
Some trials
| Journal article, free access |
| GET 2014. Stimulation of soluble guanylate cyclase prevents cigarette smoke-induced pulmonary hypertension and emphysema Extract PDF direct |
| Journal article, free access |
| GET 2015. Acute effects of riociguat in borderline or manifest pulmonary hypertension associated with chronic obstructive pulmonary disease Extract PDF direct |
| Journal article, free access |
| GET 2015. Change of right heart size and function by long-term therapy with riociguat in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension Extract PDF direct |
| Journal article, free access |
| GET 2011. Soluble guanylate cyclase stimulation prevents fibrotic tissue remodeling and improves survival in salt-sensitive Dahl rats Extract PDF direct |
Books
