Template:Dgfn2015 Mo 7:00 PCSK9 - HOP house of papers

Revision as of 18:43, 14 September 2015 (view source)

Ossip Groth (Talk | contribs)

← Older edit

Revision as of 19:01, 14 September 2015 (view source)

Ossip Groth (Talk | contribs)

Newer edit →

Line 1:

−

~~''dataset not ready 30 citations remianig'''~~

+

[http://nephrologie.conference2web.com/contentsessions/1945 DGFN2015 Neue Wirkansätze in der Hyperlipidämie - Stellenwert für die Nephrologie (Rump-LC,Gouni-Berthold-I)] see session video

+

==Lipidmanagement bei CKD-Patienten, Was ist belegt, was zu beachten. (Wanner-W)==

{{utp|p=12612979|t=A controlled, prospective study of the effects of atorvastatin on proteinuria and progression of kidney disease |pdf=http://linkinghub.elsevier.com/retrieve/pii/S0272-6386%2802%2969247-9?showall=true|usr=|}}

Line 8:

Line 9:

{{utp|p=16214597|t=Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins |pdf=http://linkinghub.elsevier.com/retrieve/pii/S0140-6736%2805%2967394-1?showall=true|usr=|}}

+

==PCSK9-Inhibitoren: ein neuer Wirkmechanismus (Schettler-V)==

{{utp|p=25815993|t=A century of cholesterol and coronaries: from plaques to genes to statins |pdf=http://www.cell.com/cell/abstract/S0092-8674%2815%2900079-3?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867415000793%3Fshowall%3Dtrue|usr=|}}

Line 57:

Line 60:

{{tp|p=25915661|t=Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis |pdf=http://annals.org/data/Journals/AIM/934197/0000605-201507070-00009.pdf|usr=|}}

+

==Was kommt nach den Statinen ? Aktuelles zu PCSK9 Antikörpern (König-W)==

+

{{tp|p=25082583|t=Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials |pdf=http://linkinghub.elsevier.com/retrieve/pii/S0735-1097(14)02704-1|usr=|}}

+

{{utp|p=20102893|t=Meta-analysis of comparative efficacy of incre

@@ Line 1: / Line 1: @@
-''dataset not ready 30 citations remianig'''
+[http://nephrologie.conference2web.com/contentsessions/1945 DGFN2015 Neue Wirkansätze in der Hyperlipidämie - Stellenwert für die Nephrologie (Rump-LC,Gouni-Berthold-I)] see session video
+==Lipidmanagement bei CKD-Patienten, Was ist belegt, was zu beachten. (Wanner-W)==
 {{utp|p=12612979|t=A controlled, prospective study of the effects of atorvastatin on proteinuria and progression of kidney disease |pdf=http://linkinghub.elsevier.com/retrieve/pii/S0272-6386%2802%2969247-9?showall=true|usr=|}}
@@ Line 8: / Line 9: @@
 {{utp|p=16214597|t=Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis  of data from 90,056 participants in 14 randomised trials of statins |pdf=http://linkinghub.elsevier.com/retrieve/pii/S0140-6736%2805%2967394-1?showall=true|usr=|}}
+==PCSK9-Inhibitoren: ein neuer Wirkmechanismus (Schettler-V)==
 {{utp|p=25815993|t=A century of cholesterol and coronaries: from plaques to genes to statins |pdf=http://www.cell.com/cell/abstract/S0092-8674%2815%2900079-3?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867415000793%3Fshowall%3Dtrue|usr=|}}
@@ Line 57: / Line 60: @@
 {{tp|p=25915661|t=Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis |pdf=http://annals.org/data/Journals/AIM/934197/0000605-201507070-00009.pdf|usr=|}}
+==Was kommt nach den Statinen ? Aktuelles zu PCSK9 Antikörpern (König-W)==
+{{tp|p=25082583|t=Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials |pdf=http://linkinghub.elsevier.com/retrieve/pii/S0735-1097(14)02704-1|usr=|}}
+{{utp|p=20102893|t=Meta-analysis of comparative efficacy of incre&#160;</td><td class='diff-marker'>+</td><td class='diff-addedline'><div><ins class="diffchange"></ins></div></td></tr>
<tr><td colspan="2">&#160;</td><td class='diff-marker'>+</td><td class='diff-addedline'><div><ins class="diffchange">{{utp|p=25773607|t=Efficacy and safety of evolocumab in reducing lipids and cardiovascular events |pdf=http://www.nejm.org/doi/full/10.1056/NEJMoa1500858|usr=|}}</ins></div></td></tr>
</table><hr class='diff-hr' />
		<h2 class='diff-currentversion-title'>Revision as of 19:01, 14 September 2015</h2>
<p><a rel="nofollow" class="external text" href="http://nephrologie.conference2web.com/contentsessions/1945">DGFN2015 Neue Wirkansätze in der Hyperlipidämie - Stellenwert für die Nephrologie (Rump-LC,Gouni-Berthold-I)</a> see session video
</p>
<h2> <span class="mw-headline" id="Lipidmanagement_bei_CKD-Patienten.2C_Was_ist_belegt.2C_was_zu_beachten._.28Wanner-W.29">Lipidmanagement bei CKD-Patienten, Was ist belegt, was zu beachten. (Wanner-W)</span></h2>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=12612979&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>A controlled, prospective study of the effects of atorvastatin on proteinuria and progression of kidney disease</b> <a href="/hop/index.php?title=Expm12612979&amp;action=edit&amp;redlink=1" class="new" title="Expm12612979 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://linkinghub.elsevier.com/retrieve/pii/S0272-6386%2802%2969247-9?showall=true"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=26331409&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Implementation of the KDIGO guideline on lipid management requires a substantial  increase in statin prescription rates</b> <a href="/hop/index.php?title=Expm26331409&amp;action=edit&amp;redlink=1" class="new" title="Expm26331409 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.nature.com/ki/journal/vaop/ncurrent/full/ki2015246a.html"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=19068318&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia</b> <a href="/hop/index.php?title=Expm19068318&amp;action=edit&amp;redlink=1" class="new" title="Expm19068318 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://linkinghub.elsevier.com/retrieve/pii/S0002-9149%2808%2901833-X?showall=true"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=16214597&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis  of data from 90,056 participants in 14 randomised trials of statins</b> <a href="/hop/index.php?title=Expm16214597&amp;action=edit&amp;redlink=1" class="new" title="Expm16214597 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://linkinghub.elsevier.com/retrieve/pii/S0140-6736%2805%2967394-1?showall=true"><b>PDF direct</b></a>
</td></tr></table>
<h2> <span class="mw-headline" id="PCSK9-Inhibitoren:_ein_neuer_Wirkmechanismus_.28Schettler-V.29">PCSK9-Inhibitoren: ein neuer Wirkmechanismus (Schettler-V)</span></h2>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=25815993&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>A century of cholesterol and coronaries: from plaques to genes to statins</b> <a href="/hop/index.php?title=Expm25815993&amp;action=edit&amp;redlink=1" class="new" title="Expm25815993 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.cell.com/cell/abstract/S0092-8674%2815%2900079-3?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867415000793%3Fshowall%3Dtrue"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=24160703&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Targeting PCSK9 for hypercholesterolemia</b> <a href="/hop/index.php?title=Expm24160703&amp;action=edit&amp;redlink=1" class="new" title="Expm24160703 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.annualreviews.org/doi/abs/10.1146/annurev-pharmtox-011613-140025?url_ver=Z39.88-2003&amp;rfr_dat=cr_pub%3Dpubmed&amp;rfr_id=ori%3Arid%3Acrossref.org&amp;journalCode=pharmtox"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=22679642&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>The biology and therapeutic targeting of the proprotein convertases</b> <a href="/hop/index.php?title=Expm22679642&amp;action=edit&amp;redlink=1" class="new" title="Expm22679642 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.nature.com/nrd/journal/v11/n5/full/nrd3699.html"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=26195630&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Plasma membrane CD81 complexes with PCSK9 and LDLR and its levels are reduced by  PCSK9</b> <a href="/hop/index.php?title=Expm26195630&amp;action=edit&amp;redlink=1" class="new" title="Expm26195630 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.jbc.org/content/early/2015/07/20/jbc.M115.642991.full.pdf"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=16554535&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Protease variants, LDL, and coronary heart disease</b> <a href="/hop/index.php?title=Expm16554535&amp;action=edit&amp;redlink=1" class="new" title="Expm16554535 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.nejm.org/doi/full/10.1056/NEJMe068026"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=17200716&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia</b> <a href="/hop/index.php?title=Expm17200716&amp;action=edit&amp;redlink=1" class="new" title="Expm17200716 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.jci.org/articles/view/29415/pdf"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=12730697&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Mutations in PCSK9 cause autosomal dominant hypercholesterolemia</b> <a href="/hop/index.php?title=Expm12730697&amp;action=edit&amp;redlink=1" class="new" title="Expm12730697 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.nature.com/ng/journal/v34/n2/full/ng1161.html"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=23973703&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Targeting the proprotein convertase subtilisin/kexin type 9 for the treatment of  dyslipidemia and atherosclerosis</b> <a href="/hop/index.php?title=Expm23973703&amp;action=edit&amp;redlink=1" class="new" title="Expm23973703 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://linkinghub.elsevier.com/retrieve/pii/S0735-1097(13)03099-4"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=19191301&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Mutations and polymorphisms in the proprotein convertase subtilisin kexin 9 (PCSK9) gene in cholesterol metabolism and disease</b> <a href="/hop/index.php?title=Expm19191301&amp;action=edit&amp;redlink=1" class="new" title="Expm19191301 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://onlinelibrary.wiley.com/doi/10.1002/humu.20882/pdf"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=16554528&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Sequence variations in PCSK9, low LDL, and protection against coronary heart disease</b> <a href="/hop/index.php?title=Expm16554528&amp;action=edit&amp;redlink=1" class="new" title="Expm16554528 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.nejm.org/doi/pdf/10.1056/NEJMoa054013"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=20031607&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Longitudinal association of PCSK9 sequence variations with low-density lipoprotein cholesterol levels: the Coronary Artery Risk Development in Young Adults Study</b> <a href="/hop/index.php?title=Expm20031607&amp;action=edit&amp;redlink=1" class="new" title="Expm20031607 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://circgenetics.ahajournals.org/content/2/4/354.full.pdf+html"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=24115837&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>The biology of PCSK9 from the endoplasmic reticulum to lysosomes: new and emerging therapeutics to control low-density lipoprotein cholesterol</b> <a href="/hop/index.php?title=Expm24115837&amp;action=edit&amp;redlink=1" class="new" title="Expm24115837 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="https://www.dovepress.com/getfile.php?fileID=17713"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=22811413&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>The PCSK9 decade</b> <a href="/hop/index.php?title=Expm22811413&amp;action=edit&amp;redlink=1" class="new" title="Expm22811413 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.jlr.org/content/53/12/2515.full.pdf"><b>PDF direct</b></a>
</td></tr></table>
<p><br />
</p>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=24407047&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Antihyperlipidemic therapies targeting PCSK9</b> <a href="/hop/index.php?title=Expm24407047&amp;action=edit&amp;redlink=1" class="new" title="Expm24407047 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://journals.lww.com/cardiologyinreview/Abstract/2014/05000/Antihyperlipidemic_Therapies_Targeting_PCSK9.4.aspx"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=23959229&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Pharmacotherapies for lipid modification: beyond the statins</b> <a href="/hop/index.php?title=Expm23959229&amp;action=edit&amp;redlink=1" class="new" title="Expm23959229 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://dx.doi.org/10.1038/nrcardio.2013.117"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=15972289&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Lipids and CVD management: towards a global consensus</b> <a href="/hop/index.php?title=Expm15972289&amp;action=edit&amp;redlink=1" class="new" title="Expm15972289 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://eurheartj.oxfordjournals.org/content/ehj/26/21/2224.full.pdf"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=20525997&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>High-dose atorvastatin causes a rapid sustained increase in human serum PCSK9 and disrupts its correlation with LDL cholesterol</b> <a href="/hop/index.php?title=Expm20525997&amp;action=edit&amp;redlink=1" class="new" title="Expm20525997 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.jlr.org/content/51/9/2714.full.pdf+html"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=25659873&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>The role of PCSK9 in intestinal lipoprotein metabolism: synergism of statin and ezetimibe</b> <a href="/hop/index.php?title=Expm25659873&amp;action=edit&amp;redlink=1" class="new" title="Expm25659873 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.sciencedirect.com/science/article/pii/S1567568815500068"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=24678979&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>A 52-week placebo-controlled trial of evolocumab in hyperlipidemia</b> <a href="/hop/index.php?title=Expm24678979&amp;action=edit&amp;redlink=1" class="new" title="Expm24678979 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.nejm.org/doi/pdf/10.1056/NEJMoa1316222"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=25282520&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia  (TESLA Part B): a randomised, double-blind, placebo-controlled trial</b> <a href="/hop/index.php?title=Expm25282520&amp;action=edit&amp;redlink=1" class="new" title="Expm25282520 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.sciencedirect.com/science/article/pii/S014067361461374X"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=23884353&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>AMG145, a monoclonal antibody against proprotein convertase subtilisin kexin type 9, significantly reduces lipoprotein(a) in hypercholesterolemic patients receiving statin therapy: an analysis from the LDL-C Assessment with Proprotein Convertase Subtilisin Kexin Type 9 Monoclonal Antibody Inhibition Combined with Statin Therapy (LAPLACE)-Thrombolysis in Myocardial Infarction (TIMI) 57 trial</b> <a href="/hop/index.php?title=Expm23884353&amp;action=edit&amp;redlink=1" class="new" title="Expm23884353 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://circ.ahajournals.org/content/128/9/962.full.pdf"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=25499936&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Lipoprotein(a) mass: a massively misunderstood metric</b> <a href="/hop/index.php?title=Expm25499936&amp;action=edit&amp;redlink=1" class="new" title="Expm25499936 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.sciencedirect.com/science/article/pii/S1933287414003079"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access <i>(Hinweis: wrong paper&#160;??? 2015;15:41 Schettler)</i>
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=25652812&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Impact of the German Lipoprotein Apheresis Registry (DLAR) on therapeutic options to reduce increased Lp(a) levels</b> <a href="/hop/index.php?title=Expm25652812&amp;action=edit&amp;redlink=1" class="new" title="Expm25652812 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://link.springer.com/content/pdf/10.1007%2Fs11789-015-0073-1.pdf"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=25915661&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis</b> <a href="/hop/index.php?title=Expm25915661&amp;action=edit&amp;redlink=1" class="new" title="Expm25915661 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://annals.org/data/Journals/AIM/934197/0000605-201507070-00009.pdf"><b>PDF direct</b></a>
</td></tr></table>
<h2> <span class="mw-headline" id="Was_kommt_nach_den_Statinen_.3F_Aktuelles_zu_PCSK9_Antik.C3.B6rpern_.28K.C3.B6nig-W.29">Was kommt nach den Statinen&#160;? Aktuelles zu PCSK9 Antikörpern (König-W)</span></h2>
<table style="border: 1pt">

<tr>
<td style="background:#E6E6F0; width:50em; color:#000000"> Journal article, free access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=25082583&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials</b> <a href="/hop/index.php?title=Expm25082583&amp;action=edit&amp;redlink=1" class="new" title="Expm25082583 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://linkinghub.elsevier.com/retrieve/pii/S0735-1097(14)02704-1"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=20102893&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Meta-analysis of comparative efficacy of incre<iframe src="http://www.kidney.de/amapp.php?a=g dose of Atorvastatin versus Rosuvastatin versus Simvastatin on lowering levels of atherogenic lipids (from VOYAGER)</b> <a href="/hop/index.php?title=Expm20102893&amp;action=edit&amp;redlink=1" class="new" title="Expm20102893 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.sciencedirect.com/science/article/pii/S0002914909022164"><b>PDF direct</b></a>
</td></tr></table>
<table style="border: 1pt">

<tr>
<td style="background:#ffffff; width:50em; color:#000000"> Journal Paper, restricted access
</td></tr>
<tr>
<td style="background:#FFFFFF; width:50em"> <a rel="nofollow" class="external text" href="http://www.kidney.de/pget.php?pmid=25773607&amp;px1=proxy.nationallizenzen.de&amp;px2=&amp;px3=&amp;px4=he&amp;"><b>GET</b></a> <b>Efficacy and safety of evolocumab in reducing lipids and cardiovascular events</b> <a href="/hop/index.php?title=Expm25773607&amp;action=edit&amp;redlink=1" class="new" title="Expm25773607 (page does not exist)"> Extract</a> <a rel="nofollow" class="external text" href="http://www.nejm.org/doi/full/10.1056/NEJMoa1500858"><b>PDF direct</b></a>
</td></tr></table>
</div>				<!-- /bodycontent -->
								<!-- printfooter -->
				<div class="printfooter">
				Retrieved from "<a href="http://house-of-papers.com/hop/index.php?title=Template:Dgfn2015_Mo_7:00_PCSK9&amp;oldid=470">http://house-of-papers.com/hop/index.php?title=Template:Dgfn2015_Mo_7:00_PCSK9&amp;oldid=470</a>"				</div>
				<!-- /printfooter -->
												<!-- catlinks -->
				<div id='catlinks' class='catlinks'><div id="mw-normal-catlinks"><a href="/hop/index.php?title=Special:Categories" title="Special:Categories">Category</a>: <ul><li><a href="/hop/index.php?title=Category:Journal_Articles_Inside&amp;action=edit&amp;redlink=1" class="new" title="Category:Journal Articles Inside (page does not exist)">Journal Articles Inside</a></li></ul></div></div>				<!-- /catlinks -->
												<div class="visualClear"></div>
				<!-- debughtml -->
								<!-- /debughtml -->
			</div>
			<!-- /bodyContent -->
		</div>
		<!-- /content -->
		<!-- header -->
		<div id="mw-head" class="noprint">
			
<!-- 0 -->
<div id="p-personal" class="">
	<h5>Personal tools</h5>
	<ul>
		<li id="pt-login"><a href="/hop/index.php?title=Special:UserLogin&amp;returnto=Template%3ADgfn2015+Mo+7%3A00+PCSK9&amp;returntoquery=diff%3Dprev%26oldid%3D470" title="You are encouraged to log in; however, it is not mandatory [o]" accesskey="o">Log in</a></li>
	</ul>
</div>

<!-- /0 -->
			<div id="left-navigation">
				
<!-- 0 -->
<div id="p-namespaces" class="vectorTabs">
	<h5>Namespaces</h5>
	<ul>
					<li  id="ca-nstab-template" class="selected"><span><a href="/hop/index.php?title=Template:Dgfn2015_Mo_7:00_PCSK9"  title="View the template [c]" accesskey="c">Template</a></span></li>
					<li  id="ca-talk" class="new"><span><a href="/hop/index.php?title=Template_talk:Dgfn2015_Mo_7:00_PCSK9&amp;action=edit&amp;redlink=1"  title="Discussion about the content page [t]" accesskey="t">Discussion</a></span></li>
			</ul>
</div>

<!-- /0 -->

<!-- 1 -->
<div id="p-variants" class="vectorMenu emptyPortlet">
		<h5><span>Variants</span><a href="#"></a></h5>
	<div class="menu">
		<ul>
					</ul>
	</div>
</div>

<!-- /1 -->
			</div>
			<div id="right-navigation">
				
<!-- 0 -->
<div id="p-views" class="vectorTabs">
	<h5>Views</h5>
	<ul>
					<li id="ca-view" class="selected"><span><a href="/hop/index.php?title=Template:Dgfn2015_Mo_7:00_PCSK9" >Read</a></span></li>
					<li id="ca-viewsource"><span><a href="/hop/index.php?title=Template:Dgfn2015_Mo_7:00_PCSK9&amp;action=edit&amp;oldid=470"  title="This page is protected.&#10;You can view its source [e]" accesskey="e">View source</a></span></li>
					<li id="ca-history" class="collapsible"><span><a href="/hop/index.php?title=Template:Dgfn2015_Mo_7:00_PCSK9&amp;action=history"  title="Past revisions of this page [h]" accesskey="h">View history</a></span></li>
			</ul>
</div>

<!-- /0 -->

<!-- 1 -->
<div id="p-cactions" class="vectorMenu emptyPortlet">
	<h5><span>Actions</span><a href="#"></a></h5>
	<div class="menu">
		<ul>
					</ul>
	</div>
</div>

<!-- /1 -->

<!-- 2 -->
<div id="p-search">
	<h5><label for="searchInput">Search</label></h5>
	<form action="/hop/index.php" id="searchform">
		<input type='hidden' name="title" value="Special:Search"/>
				<input type="search" name="search" title="Search HOP house of papers [f]" accesskey="f" id="searchInput" />		<input type="submit" name="go" value="Go" title="Go to a page with this exact name if exists" id="searchGoButton" class="searchButton" />		<input type="submit" name="fulltext" value="Search" title="Search the pages for this text" id="mw-searchButton" class="searchButton" />			</form>
</div>

<!-- /2 -->
			</div>
		</div>
		<!-- /header -->
		<!-- panel -->
			<div id="mw-panel" class="noprint">
				<!-- logo -->
					<div id="p-logo"><a style="background-image: url(http://www.house-of-papers.com/img/hop2.jpg);" href="/hop/index.php?title=Main_Page"  title="Visit the main page"></a></div>
				<!-- /logo -->
				
<!-- navigation -->
<div class="portal" id='p-navigation'>
	<h5>Navigation</h5>
	<div class="body">
		<ul>
			<li id="n-mainpage-description"><a href="/hop/index.php?title=Main_Page" title="Visit the main page [z]" accesskey="z">Main page</a></li>
			<li id="n-hop-Nephrology-index"><a href="/hop/index.php?title=HOP_Nephrology_Index">hop Nephrology index</a></li>
			<li id="n-moremed-Search"><a href="/hop/index.php?title=Moremed.org">moremed Search</a></li>
		</ul>
	</div>
</div>

<!-- /navigation -->

<!-- SEARCH -->

<!-- /SEARCH -->

<!-- TOOLBOX -->
<div class="portal" id='p-tb'>
	<h5>Toolbox</h5>
	<div class="body">
		<ul>
			<li id="t-whatlinkshere"><a href="/hop/index.php?title=Special:WhatLinksHere/Template:Dgfn2015_Mo_7:00_PCSK9" title="A list of all wiki pages that link here [j]" accesskey="j">What links here</a></li>
			<li id="t-recentchangeslinked"><a href="/hop/index.php?title=Special:RecentChangesLinked/Template:Dgfn2015_Mo_7:00_PCSK9" title="Recent changes in pages linked from this page [k]" accesskey="k">Related changes</a></li>
			<li id="t-specialpages"><a href="/hop/index.php?title=Special:SpecialPages" title="A list of all special pages [q]" accesskey="q">Special pages</a></li>
			<li><a href="/hop/index.php?title=Template:Dgfn2015_Mo_7:00_PCSK9&amp;diff=prev&amp;oldid=470&amp;printable=yes" rel="alternate">Printable version</a></li>
			<li id="t-permalink"><a href="/hop/index.php?title=Template:Dgfn2015_Mo_7:00_PCSK9&amp;oldid=470" title="Permanent link to this revision of the page">Permanent link</a></li>
		</ul>
	</div>
</div>

<!-- /TOOLBOX -->

<!-- LANGUAGES -->

<!-- /LANGUAGES -->
			</div>
		<!-- /panel -->
		<!-- footer -->
		<div id="footer">
							<ul id="footer-places">
											<li id="footer-places-privacy"><a href="/hop/index.php?title=HOP_house_of_papers:Privacy_policy" title="HOP house of papers:Privacy policy">Privacy policy</a></li>
											<li id="footer-places-about"><a href="/hop/index.php?title=HOP_house_of_papers:About" title="HOP house of papers:About">About HOP house of papers</a></li>
											<li id="footer-places-disclaimer"><a href="/hop/index.php?title=HOP_house_of_papers:General_disclaimer" title="HOP house of papers:General disclaimer">Disclaimers</a></li>
									</ul>
										<ul id="footer-icons" class="noprint">
					<li id="footer-poweredbyico">
						<a href="http://www.mediawiki.org/"><img src="/hop/skins/common/images/poweredby_mediawiki_88x31.png" alt="Powered by MediaWiki" width="88" height="31" /></a>
					</li>
				</ul>
						<div style="clear:both"></div>
		</div>
		<!-- /footer -->
		<!-- fixalpha -->
		<script type="text/javascript"> if ( window.isMSIE55 ) fixalpha(); </script>
		<!-- /fixalpha -->
		<script src="/hop/load.php?debug=false&amp;lang=en&amp;modules=skins.vector&amp;only=scripts&amp;skin=vector&amp;*"></script>
<a href="http://www.bloggerei.de/rubrik_5_Kunstblogs" title="Blog-Verzeichnis"><img src="http://www.bloggerei.de/bgpublicon.jpg" width="80" height="15" border="0" alt="Blogverzeichnis - Blog Verzeichnis bloggerei.de" /></a><a href="http://www.bloggeramt.de/" title="BloggerAmt" target="_blank"><img src="http://www.bloggeramt.de/images/blog_button1.gif" style="border:0px;" alt="Blogverzeichnis" /></a><script>if(window.mw){
	mw.loader.load(["mediawiki.user", "mediawiki.util", "mediawiki.page.ready", "mediawiki.legacy.wikibits", "mediawiki.legacy.ajax"]);
}
</script>
<script src="/hop/load.php?debug=false&amp;lang=en&amp;modules=site&amp;only=scripts&amp;skin=vector&amp;*"></script>
<script>if(window.mw){
	mw.user.options.set({"ccmeonemails":0,"cols":80,"date":"default","diffonly":0,"disablemail":0,"disablesuggest":0,"editfont":"default","editondblclick":0,"editsection":1,"editsectiononrightclick":0,"enotifminoredits":0,"enotifrevealaddr":0,"enotifusertalkpages":1,"enotifwatchlistpages":0,"extendwatchlist":0,"externaldiff":0,"externaleditor":0,"fancysig":0,"forceeditsummary":0,"gender":"unknown","hideminor":0,"hidepatrolled":0,"highlightbroken":1,"imagesize":2,"justify":0,"math":1,"minordefault":0,"newpageshidepatrolled":0,"nocache":0,"noconvertlink":0,"norollbackdiff":0,"numberheadings":0,"previewonfirst":0,"previewontop":1,"quickbar":5,"rcdays":7,"rclimit":50,"rememberpassword":0,"rows":25,"searchlimit":20,"showhiddencats":0,"showjumplinks":1,"shownumberswatching":1,"showtoc":1,"showtoolbar":1,"skin":"vector","stubthreshold":0,"thumbsize":2,"underline":2,"uselivepreview":0,"usenewrc":0,"watchcreations":0,"watchdefault":0,"watchdeletion":0,"watchlistdays":3,"watchlisthideanons":0,
	"watchlisthidebots":0,"watchlisthideliu":0,"watchlisthideminor":0,"watchlisthideown":0,"watchlisthidepatrolled":0,"watchmoves":0,"wllimit":250,"variant":"en","language":"en","searchNs0":true,"searchNs1":false,"searchNs2":false,"searchNs3":false,"searchNs4":false,"searchNs5":false,"searchNs6":false,"searchNs7":false,"searchNs8":false,"searchNs9":false,"searchNs10":false,"searchNs11":false,"searchNs12":false,"searchNs13":false,"searchNs14":false,"searchNs15":false});;mw.user.tokens.set({"editToken":"+\\","watchToken":false});;mw.loader.state({"user.options":"ready","user.tokens":"ready"});
	
	/* cache key: hop-hop:resourceloader:filter:minify-js:4:19a4b18a9ac79a6b8c60b24af4668814 */
}
</script><!-- Served in 0.989 secs. -->
	</body>
</html>