Velcalcetide

From HOP house of papers
(Difference between revisions)
Jump to: navigation, search
(Created page with "{{mmst|Velcalcetide|Etelcalcetide+OR+{AMG_416}+OR+{KAI_4169}+OR+{ONO_5163}+OR+Telcalcetide+OR+Velcalcetide}}")
 
m (Trials)
 
(7 intermediate revisions by one user not shown)
Line 1: Line 1:
 +
{{hoprn||1}}
 +
 
{{mmst|Velcalcetide|Etelcalcetide+OR+{AMG_416}+OR+{KAI_4169}+OR+{ONO_5163}+OR+Telcalcetide+OR+Velcalcetide}}
 
{{mmst|Velcalcetide|Etelcalcetide+OR+{AMG_416}+OR+{KAI_4169}+OR+{ONO_5163}+OR+Telcalcetide+OR+Velcalcetide}}
 +
 +
Velcalcetide, a novel calcimimetic,  is an allosteric activator of casr, the calcium sensitizing receptor and is in development to treat secondary hyperparathyreoidism of chronical renal failure in a way similar to cinacalcet.
 +
 +
==Mechanism of action==
 +
{{slink| |t=Velcalcetide for secondary hyperparathyroidism – first line|l=http://www.hsric.nihr.ac.uk/topics/velcalcetide-for-secondary-hyperparathyroidism-first-line/|usr=goo}}
 +
{{tp|p=26290606|t=Critical Cysteine Residues in Both the Calcium-Sensing Receptor and the Allosteric Activator AMG 416 Underlie the Mechanism of Action |pdf=http://molpharm.aspetjournals.org/content/early/2015/08/19/mol.115.098392.full.pdf|usr=|}}
 +
{{tp|p=23674604|t=Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients |pdf=|usr=|}}
 +
{{tp|p=24884838|t=Comparison of AMG 416 and cinacalcet in rodent models of uremia |pdf=http://www.biomedcentral.com/content/pdf/1471-2369-15-81.pdf|usr=|}}
 +
{{tp|p=24235081|t=Velcalcetide (AMG 416), a novel peptide agonist of the calcium-sensing receptor,  reduces serum parathyroid hormone and FGF23 levels in healthy male subjects |pdf=http://ndt.oxfordjournals.org/content/29/2/385.full.pdf|usr=|}}
 +
{{tp|p=23903371|t=AMG 416 (velcalcetide) is a novel peptide for the treatment of secondary hyperparathyroidism in a single-dose study in hemodialysis patients |pdf=|usr=|}}
 +
 +
                                            
 +
 +
==Mentioned in Fulltext==
 +
{{tp|p=24578336|t=The use of fibroblast growth factor 23 testing in patients with kidney disease |pdf=http://cjasn.asnjournals.org/content/9/7/1283.full.pdf|usr=|}}
 +
{{tp|p=25878777|t=Longitudinal FGF23 and Klotho axis characterization in children treated with chronic peritoneal dialysis |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=25878777&pmc=4379333&ti=Longitudinal%20FGF23%20and%20Klotho%20axis%20characterization%20in%20children%20treated%20with%20chronic%20peritoneal%20dialysis|usr=|}}
 +
{{tp|p=25028644|t=Calcimimetics and outcomes in CKD |pdf=http://sm.kidney.de/epmc.php?ep=eu&pmid=25028644&pmc=4089624&ti=Calcimimetics%20and%20outcomes%20in%20CKD|usr=|}}
 +
 +
                                            
 +
 +
==Trials==
 +
{{slink|t=trials|l=https://www.clinicaltrials.gov/ct2/results?term=%28Etelcalcetide+OR+%28AMG-416+OR+AMG+416+OR+AMG416%29+OR+%28KAI-4169+OR+KAI+4169+OR+KAI4169%29+OR+%28ONO-5163+OR+ONO+5163+OR+ONO5163%29+OR+Telcalcetide+OR+Velcalcetide%29&Search=Search}}
 +
 +
==Wikipedia==
 +
 +
{{wiki|en=Etelcalcetide|de=|c=|}}
 +
 +
==Books==
 +

Latest revision as of 06:53, 1 September 2015

Moremed Velcalcetide Etelcalcetide+OR+{AMG_416}+OR+{KAI_4169}+OR+{ONO_5163}+OR+Telcalcetide+OR+Velcalcetide

Velcalcetide, a novel calcimimetic, is an allosteric activator of casr, the calcium sensitizing receptor and is in development to treat secondary hyperparathyreoidism of chronical renal failure in a way similar to cinacalcet.

Contents

Mechanism of action

Weblink noncommercial {{{c}}}
Velcalcetide for secondary hyperparathyroidism – first line
Journal article, free access
GET Critical Cysteine Residues in Both the Calcium-Sensing Receptor and the Allosteric Activator AMG 416 Underlie the Mechanism of Action Extract PDF direct
Journal article, free access
GET Pharmacology of AMG 416 (Velcalcetide), a novel peptide agonist of the calcium-sensing receptor, for the treatment of secondary hyperparathyroidism in hemodialysis patients Extract [ PDF direct]
Journal article, free access
GET Comparison of AMG 416 and cinacalcet in rodent models of uremia Extract PDF direct
Journal article, free access
GET Velcalcetide (AMG 416), a novel peptide agonist of the calcium-sensing receptor, reduces serum parathyroid hormone and FGF23 levels in healthy male subjects Extract PDF direct
Journal article, free access
GET AMG 416 (velcalcetide) is a novel peptide for the treatment of secondary hyperparathyroidism in a single-dose study in hemodialysis patients Extract [ PDF direct]

                                            

Mentioned in Fulltext

Journal article, free access
GET The use of fibroblast growth factor 23 testing in patients with kidney disease Extract PDF direct
Journal article, free access
GET Longitudinal FGF23 and Klotho axis characterization in children treated with chronic peritoneal dialysis Extract PDF direct
Journal article, free access
GET Calcimimetics and outcomes in CKD Extract PDF direct

                                            

Trials

Weblink noncommercial {{{c}}}
trials

Wikipedia

Wikipedia
en-wiki

Books

Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox
Blogverzeichnis - Blog Verzeichnis bloggerei.deBlogverzeichnis